I often go a couple of days without showering or changing clothes when wörking from home, yes. My hair looks greasy and shitty after just 1-2 days without washing it, but in winter for grocery shopping or a walk alone I can just put on a beanie and problems weren't :3
When I go out for more than grocery shopping, I pretty much always shower before and put on clothes that (almost) don't smell. If the armpits or crotch of my undershirt / sweatshirt / pants smell very slightly, I assume it's fine unless I am planning to sit right next to someone inside in a very smell-neutral environment (not subway or pub).